https://wiki.pymol.org/api.php?action=feedcontributions&feedformat=atom&user=Dambor 2026-06-19T12:54:16Z User contributions MediaWiki 1.35.1 https://wiki.pymol.org/index.php?title=Caver&diff=5013 2007-06-28T14:36:57Z

<p>Dambor: New page: [http://loschmidt.chemi.muni.cz/caver/index.php CAVER] provides rapid, accurate and fully automated calculation of pathways leading from buried cavities to outside solvent in static and dy...</p> <hr /> <div>[http://loschmidt.chemi.muni.cz/caver/index.php CAVER] provides rapid, accurate and fully automated calculation of pathways leading from buried cavities to outside solvent in static and dynamic protein structures. Study of these pathways is important in drug design and molecular enzymology to understand binding of inhibitors to the receptors, substrate binding and product egress from the enzyme active sites. Calculated pathways can be visualized by graphic program PyMol dissecting anatomy and dynamics of entrance tunnels. CAVER allows analysis of any molecular structure including proteins, nucleic acids, inorganic materials, etc.<br /> <br /> References:<br /> <br /> Petřek M., Otyepka M., Banáš P., Košinová P., Koča J. and Damborský J., [http://loschmidt.chemi.muni.cz/peg/abstracts/bmcbioinf06.html CAVER: A New Tool to Explore Routes from Protein Clefts, Pockets and Cavities], BMC Bioinformatics 2006, 7: 316<br /> <br /> Damborský J., Petřek M., Banáš P., Otyepka M., [http://loschmidt.chemi.muni.cz/peg/abstracts/btj07a.html Identification of Tunnels in Proteins, Nucleic Acids, Inorganic Materials and Molecular Ensembles], Biotechnology Journal 2007, 2: 62-67 <br /> <br /> <br /> [[Image:Caver.png]]</div>

Dambor https://wiki.pymol.org/index.php?title=User_talk:Dambor&diff=10737 2007-06-28T14:35:07Z

<p>Dambor: New page: [http://loschmidt.chemi.muni.cz/caver/index.php CAVER] provides rapid, accurate and fully automated calculation of pathways leading from buried cavities to outside solvent in static and dy...</p> <hr /> <div>[http://loschmidt.chemi.muni.cz/caver/index.php CAVER] provides rapid, accurate and fully automated calculation of pathways leading from buried cavities to outside solvent in static and dynamic protein structures. Study of these pathways is important in drug design and molecular enzymology to understand binding of inhibitors to the receptors, substrate binding and product egress from the enzyme active sites. Calculated pathways can be visualized by graphic program PyMol dissecting anatomy and dynamics of entrance tunnels. CAVER allows analysis of any molecular structure including proteins, nucleic acids, inorganic materials, etc.<br /> <br /> References:<br /> <br /> Petřek M., Otyepka M., Banáš P., Košinová P., Koča J. and Damborský J., [http://loschmidt.chemi.muni.cz/peg/abstracts/bmcbioinf06.html CAVER: A New Tool to Explore Routes from Protein Clefts, Pockets and Cavities], BMC Bioinformatics 2006, 7: 316<br /> <br /> Damborský J., Petřek M., Banáš P., Otyepka M., [http://loschmidt.chemi.muni.cz/peg/abstracts/btj07a.html Identification of Tunnels in Proteins, Nucleic Acids, Inorganic Materials and Molecular Ensembles], Biotechnology Journal 2007, 2: 62-67 <br /> <br /> <br /> [[Image:Caver.png]]</div>

Dambor https://wiki.pymol.org/index.php?title=File:Caver.png&diff=1675 2007-06-28T14:25:29Z

<p>Dambor: </p> <hr /> <div></div>

Dambor